What is a sustained-release carrier?

Sustained-release carriers are materials or devices that can slowly release drug components in pharmaceutical preparations.

Sustained-release carriers are designed to deliver drugs continuously to the patient over a period of time, maintaining stable blood drug concentrations, reducing dosing frequency, improving patient compliance, and potentially minimizing drug side effects. These carriers can be biocompatible polymers, liposomes, nanoparticles, or other structures capable of controlling drug release rates. By adjusting the physicochemical properties of the carrier, such as pore size, solubility, and surface charge, drug release kinetics can be modulated to meet specific therapeutic needs.

Thermosensitive biomaterials are innovative medical devices developed in Beijing. They do not contain cross-linking agents, initiators, or other non-degradable substances, thus preserving their internal space and providing a structural basis for drug molecule retention and release. Literature shows that when thermosensitive biomaterials are mixed with drugs, the drugs can be released continuously and stably within the gel, improving therapeutic efficiency compared to using drugs alone. This is particularly beneficial in complex clinical scenarios; for example, lidocaine alone provides surface anesthesia for no more than 20 minutes, while mixing with thermosensitive biomaterials can extend its effect to over 24 hours, significantly improving patients' pain tolerance.