Application of temperature-sensitive biomaterial "Smart Protective Adhesive" in the field of anorectal surgery

Dr. Jing Tao, a proctologist at Dongzhimen Hospital of Beijing University of Chinese Medicine, shares a case study on the application of the thermosensitive biomaterial 'Smart Protective Adhesive' in anorectal surgical wounds.
Due to the specific location, continuous movement, and open wounds after surgery, postoperative wound care in anorectal surgery has always been a key clinical focus. Clinically, there is a need for bio-dressings with good adhesion, complete coverage, hemostasis, anti-inflammatory and antibacterial properties, and analgesia to protect the wound.

Currently, liquid dressings, gel dressings, and ointments are commonly used in clinical practice to protect wounds. Liquids lose moisture quickly and cannot form a barrier, gels have poor diffusion and cannot completely cover the wound, and ointments are highly irritating and increase patient discomfort.

Thermosensitive biomaterials are characterized by their ability to transform from liquid to gel. In their liquid state, they diffuse well and completely cover the wound. Under body temperature, they rapidly transform into a gel, exhibiting strong adhesion and being unaffected by defecation. Once the gel forms a protective barrier around the wound, it prevents external irritants such as fecal residue, thus reducing pain. Its excellent permeability allows it to function as a sustained-release carrier; for example, when mixed with lidocaine, it prolongs analgesia time and helps patients tolerate pain. It also possesses good hemostatic, anti-inflammatory, and antibacterial effects. The product is naturally biodegradable and absorbable, non-irritating, and easy to use.